PRELIMINARY PROGRAM
Wednesday PM
16:00 – 16:15 Welcome
Session 1: Phosphoinositide signaling in health and human disease I (Chair: TBD)
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16:15 – 16:45 Mariona Graupera (Josep Carreras Leukaemia Research Institute (Barcelona, Spain)
"Behaviours of cancer-associated PI3K mutations in congenital mosaic syndromes"
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16:45 – 17:15 Lloyd Trotman (Cold Spring Harbor Laboratory, Cold Spring Harbor, USA)
"Redox control of endocytosis for metastatic cancer therapy"
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17:15 – 17:30 1x Research talk selected from abstracts
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17:30 – 18:00 Lois Weisman (Life Sciences Institute, University of Michigan, USA)
"A phosphoinositide, a pentamer, a prediction: Insights into neurodegenerative diseases"
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18:00 – 18:30 2x Research talks selected from abstracts
18:30 – 20:00 Dinner
20:00 – 21:00 The Jacques E. Dumont keynote lecture (Chair: TBD)
Bart Vanhaesebroeck (University College London, London, UK)
“Exploring PI3K activation as a new avenue for therapeutic intervention”
21:00 Networking and discussion
Thursday AM
Session 2: Phosphoinositides in membrane contact site function (Chair: TBD)
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09:00 – 09:30 Jen Liou (Department of Physiology, UT Southwestern Medical Center, Dallas, USA)
“Phosphoinositide Signaling at Membrane Contact Sites”
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09:30 – 10:00 2x Research talks selected from abstracts
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10:00 – 10:30 Emmanuelle Bayer (Laboratoire de Biogenèse Membranaire, Université de Bordeaux, France)
"Crossing boundaries: Cell-cell Communication through membrane contact sites"
10:30 – 11:00 Coffee break
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11:00 – 12:00 4x Research talks selected from abstracts
12:00- 14:00 Lunch
Friday AM
Session 3: Molecular insights into inositol signaling (Chair: TBD)
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09:00 – 09:30 Vytas Bankaitis (Texas A&M Health Science Center, College Station, USA)
"An Atomistic Description of Lipid Exchange by a phosphatidylinositol Transfer Protein"
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09:30 – 10:00 John Burke (University of Victoria, Victoria, Canada)
"Novel regulatory mechanisms that control membrane recruitment of the phosphoinositide kinases"
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10:00 – 10:30 2x Research talks selected from abstracts
10:30 – 11:00 Coffee break
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11:00 – 11:30 Jim Hurley (University of California, Berkeley, USA)
"Writing and reading the PI3P signal in autophagy"
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11:30 – 12:00 Dorothea Fiedler (Leibniz Institute fur Molecular Pharmacologie, Berlin, Germany)
“The multiple modes of action of inositol pyrophosphate messengers”
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12:00 – 12:30 2 x Research talks selected from abstracts
12:30 - 14:00 Lunch
Thursday PM
14:00 – 18:30
Networking
18:30 – 20:00 Dinner
20:00 – 21:00 Keynote lecture (Chair: TBD)
Len Stephens (Babraham Institute, Cambridge, UK)
“to be announced”
21:00 Poster Session 1
Friday PM
Session 4: "Phosphoinositide signaling in nuclear functions and genome integrity" (Chair: TBD)
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14:00 – 14:30 Ganna Panasyuk (Institut Necker-Enfants Malades (INEM), Paris, France)
"Class 3 PI3K and PI3P: From cytosolic roles to nuclear transcription"
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14:30 – 15:00 Emilio Hirsch (University of Torino, Torino, Italy)
" Spatial Control of Phosphoinositides Safeguards Cytokinesis and Genome Integrity"
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15:00 – 15:30 2x Research talks selected from abstracts
15:30 – 16:00 Coffee break
Session 5: Phosphoinositide signaling in health and human disease II (Chair: TBD)
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16:00 – 16:30 Julien Viaud (Institute of Metabolic and Cardiovascular Diseases (I2MC), Inserm UMR1297, Toulouse, France)
"MTM1-dependent phosphoinositide remodeling regulates endosomal trafficking and integrin dynamics in XLMTM"
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16:30 – 17:00 Volker Haucke (Leibniz Institute fur Molecular Pharmacologie, Berlin, Germany)
"Lipid signaling in health and disease: From organelles to brain function"
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17:00 – 17:45 (18:00) 3(4)x Research talks selected from abstracts
18:30- 20:00 Dinner
20:00 – 21:00 Keynote lecture (Chair: TBD)
Maria Antonietta De Matteis (Telethon Institute of Genetics and Medicine, TIGEM, Pozzuoli, Naples, Italy)
"A PIPeline for drug discovery in Lowe syndrome"
21:00 Poster Session 2
Saturday AM
Session 6: Phosphoinositide signaling in health and human disease III (Chair: TBD)
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9:00 – 09:30 Gerry Hammond (University of Pittsburgh School of Medicine, Pittsburgh, USA)
"Mechanisms of PI(4,5)P2 homeostasis in the plasma membrane"
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9:30 – 10:15 3x Research talks selected from abstracts
10:15– 10:45 Coffee break
10:45– 11:45 Keynote lecture (Chair: TBD)
Takehiko Sasaki (Medical Research Laboratory, Institute of Science Tokyo, Tokyo, Japan)
“Phosphoinositide Remodeling as a Regulatory Axis in Aging and Disease”
11:45 - 12:15 Poster awards ceremony
& conclusions
Picnic pickup and departure at 13:00
